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\frac{\left(-32xy\right)^{2}}{\left(25+16y^{2}\right)^{2}}-\frac{4\left(16x^{2}-400\right)}{25+16y^{2}}
To raise \frac{-32xy}{25+16y^{2}} to a power, raise both numerator and denominator to the power and then divide.
\frac{\left(-32xy\right)^{2}}{\left(25+16y^{2}\right)^{2}}-\frac{64x^{2}-1600}{25+16y^{2}}
Use the distributive property to multiply 4 by 16x^{2}-400.
\frac{\left(-32xy\right)^{2}}{\left(16y^{2}+25\right)^{2}}-\frac{\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(25+16y^{2}\right)^{2} and 25+16y^{2} is \left(16y^{2}+25\right)^{2}. Multiply \frac{64x^{2}-1600}{25+16y^{2}} times \frac{16y^{2}+25}{16y^{2}+25}.
\frac{\left(-32xy\right)^{2}-\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}}
Since \frac{\left(-32xy\right)^{2}}{\left(16y^{2}+25\right)^{2}} and \frac{\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}} have the same denominator, subtract them by subtracting their numerators.
\frac{\left(-32xy\right)^{2}-1024x^{2}y^{2}-1600x^{2}+25600y^{2}+40000}{\left(16y^{2}+25\right)^{2}}
Do the multiplications in \left(-32xy\right)^{2}-\left(64x^{2}-1600\right)\left(16y^{2}+25\right).
\frac{25600y^{2}-1600x^{2}+40000}{\left(16y^{2}+25\right)^{2}}
Combine like terms in \left(-32xy\right)^{2}-1024x^{2}y^{2}-1600x^{2}+25600y^{2}+40000.
\frac{25600y^{2}-1600x^{2}+40000}{256y^{4}+800y^{2}+625}
Expand \left(16y^{2}+25\right)^{2}.
\frac{\left(-32xy\right)^{2}}{\left(25+16y^{2}\right)^{2}}-\frac{4\left(16x^{2}-400\right)}{25+16y^{2}}
To raise \frac{-32xy}{25+16y^{2}} to a power, raise both numerator and denominator to the power and then divide.
\frac{\left(-32xy\right)^{2}}{\left(25+16y^{2}\right)^{2}}-\frac{64x^{2}-1600}{25+16y^{2}}
Use the distributive property to multiply 4 by 16x^{2}-400.
\frac{\left(-32xy\right)^{2}}{\left(16y^{2}+25\right)^{2}}-\frac{\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(25+16y^{2}\right)^{2} and 25+16y^{2} is \left(16y^{2}+25\right)^{2}. Multiply \frac{64x^{2}-1600}{25+16y^{2}} times \frac{16y^{2}+25}{16y^{2}+25}.
\frac{\left(-32xy\right)^{2}-\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}}
Since \frac{\left(-32xy\right)^{2}}{\left(16y^{2}+25\right)^{2}} and \frac{\left(64x^{2}-1600\right)\left(16y^{2}+25\right)}{\left(16y^{2}+25\right)^{2}} have the same denominator, subtract them by subtracting their numerators.
\frac{\left(-32xy\right)^{2}-1024x^{2}y^{2}-1600x^{2}+25600y^{2}+40000}{\left(16y^{2}+25\right)^{2}}
Do the multiplications in \left(-32xy\right)^{2}-\left(64x^{2}-1600\right)\left(16y^{2}+25\right).
\frac{25600y^{2}-1600x^{2}+40000}{\left(16y^{2}+25\right)^{2}}
Combine like terms in \left(-32xy\right)^{2}-1024x^{2}y^{2}-1600x^{2}+25600y^{2}+40000.
\frac{25600y^{2}-1600x^{2}+40000}{256y^{4}+800y^{2}+625}
Expand \left(16y^{2}+25\right)^{2}.