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16x^{2}+8x+1-\left(4x\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(4x+1\right)^{2}.
16x^{2}+8x+1-4^{2}x^{2}
Expand \left(4x\right)^{2}.
16x^{2}+8x+1-16x^{2}
Calculate 4 to the power of 2 and get 16.
8x+1
Combine 16x^{2} and -16x^{2} to get 0.
16x^{2}+8x+1-\left(4x\right)^{2}
Use binomial theorem \left(a+b\right)^{2}=a^{2}+2ab+b^{2} to expand \left(4x+1\right)^{2}.
16x^{2}+8x+1-4^{2}x^{2}
Expand \left(4x\right)^{2}.
16x^{2}+8x+1-16x^{2}
Calculate 4 to the power of 2 and get 16.
8x+1
Combine 16x^{2} and -16x^{2} to get 0.