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4x-16+x^{2}-4x-\left(x-3\right)\left(x-5\right)
Apply the distributive property by multiplying each term of 4+x by each term of x-4.
-16+x^{2}-\left(x-3\right)\left(x-5\right)
Combine 4x and -4x to get 0.
-16+x^{2}-\left(x^{2}-5x-3x+15\right)
Apply the distributive property by multiplying each term of x-3 by each term of x-5.
-16+x^{2}-\left(x^{2}-8x+15\right)
Combine -5x and -3x to get -8x.
-16+x^{2}-x^{2}-\left(-8x\right)-15
To find the opposite of x^{2}-8x+15, find the opposite of each term.
-16+x^{2}-x^{2}+8x-15
The opposite of -8x is 8x.
-16+8x-15
Combine x^{2} and -x^{2} to get 0.
-31+8x
Subtract 15 from -16 to get -31.
4x-16+x^{2}-4x-\left(x-3\right)\left(x-5\right)
Apply the distributive property by multiplying each term of 4+x by each term of x-4.
-16+x^{2}-\left(x-3\right)\left(x-5\right)
Combine 4x and -4x to get 0.
-16+x^{2}-\left(x^{2}-5x-3x+15\right)
Apply the distributive property by multiplying each term of x-3 by each term of x-5.
-16+x^{2}-\left(x^{2}-8x+15\right)
Combine -5x and -3x to get -8x.
-16+x^{2}-x^{2}-\left(-8x\right)-15
To find the opposite of x^{2}-8x+15, find the opposite of each term.
-16+x^{2}-x^{2}+8x-15
The opposite of -8x is 8x.
-16+8x-15
Combine x^{2} and -x^{2} to get 0.
-31+8x
Subtract 15 from -16 to get -31.