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Evaluate
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Differentiate w.r.t. x
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4x^{4-1}-2x^{-2-1}-4\times 4x^{-4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
4x^{3}-2x^{-2-1}-4\times 4x^{-4-1}
Subtract 1 from 4.
4x^{3}-2x^{-3}-4\times 4x^{-4-1}
Subtract 1 from -2.
4x^{3}-2x^{-3}-16x^{-4-1}
Multiply -2 times 1.
4x^{3}-2x^{-3}-16x^{-5}
Subtract 1 from -4.