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Differentiate w.r.t. x
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\frac{x}{x+4}+\frac{3\left(x+4\right)}{x+4}-\frac{3x}{x-1}
To add or subtract expressions, expand them to make their denominators the same. Multiply 3 times \frac{x+4}{x+4}.
\frac{x+3\left(x+4\right)}{x+4}-\frac{3x}{x-1}
Since \frac{x}{x+4} and \frac{3\left(x+4\right)}{x+4} have the same denominator, add them by adding their numerators.
\frac{x+3x+12}{x+4}-\frac{3x}{x-1}
Do the multiplications in x+3\left(x+4\right).
\frac{4x+12}{x+4}-\frac{3x}{x-1}
Combine like terms in x+3x+12.
\frac{\left(4x+12\right)\left(x-1\right)}{\left(x-1\right)\left(x+4\right)}-\frac{3x\left(x+4\right)}{\left(x-1\right)\left(x+4\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x+4 and x-1 is \left(x-1\right)\left(x+4\right). Multiply \frac{4x+12}{x+4} times \frac{x-1}{x-1}. Multiply \frac{3x}{x-1} times \frac{x+4}{x+4}.
\frac{\left(4x+12\right)\left(x-1\right)-3x\left(x+4\right)}{\left(x-1\right)\left(x+4\right)}
Since \frac{\left(4x+12\right)\left(x-1\right)}{\left(x-1\right)\left(x+4\right)} and \frac{3x\left(x+4\right)}{\left(x-1\right)\left(x+4\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{4x^{2}-4x+12x-12-3x^{2}-12x}{\left(x-1\right)\left(x+4\right)}
Do the multiplications in \left(4x+12\right)\left(x-1\right)-3x\left(x+4\right).
\frac{x^{2}-4x-12}{\left(x-1\right)\left(x+4\right)}
Combine like terms in 4x^{2}-4x+12x-12-3x^{2}-12x.
\frac{x^{2}-4x-12}{x^{2}+3x-4}
Expand \left(x-1\right)\left(x+4\right).