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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{56yz^{4}}{48z^{1}y^{2}}x^{3-5})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{7z^{3}}{6y}x^{-2})
Do the arithmetic.
-2\times \frac{7z^{3}}{6y}x^{-2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{7z^{3}}{3y}\right)x^{-3}
Do the arithmetic.
\frac{7z^{3}}{6yx^{2}}
Cancel out 8yzx^{3} in both numerator and denominator.