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12x\times \frac{4}{3}+12x\left(-\frac{5}{4}\right)=12\times \frac{1}{6}
Variable x cannot be equal to 0 since division by zero is not defined. Multiply both sides of the equation by 12x, the least common multiple of 3,4,x.
\frac{12\times 4}{3}x+12x\left(-\frac{5}{4}\right)=12\times \frac{1}{6}
Express 12\times \frac{4}{3} as a single fraction.
\frac{48}{3}x+12x\left(-\frac{5}{4}\right)=12\times \frac{1}{6}
Multiply 12 and 4 to get 48.
16x+12x\left(-\frac{5}{4}\right)=12\times \frac{1}{6}
Divide 48 by 3 to get 16.
16x+\frac{12\left(-5\right)}{4}x=12\times \frac{1}{6}
Express 12\left(-\frac{5}{4}\right) as a single fraction.
16x+\frac{-60}{4}x=12\times \frac{1}{6}
Multiply 12 and -5 to get -60.
16x-15x=12\times \frac{1}{6}
Divide -60 by 4 to get -15.
x=12\times \frac{1}{6}
Combine 16x and -15x to get x.
x=\frac{12}{6}
Multiply 12 and \frac{1}{6} to get \frac{12}{6}.
x=2
Divide 12 by 6 to get 2.