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\frac{20922789888000}{8!\left(16-8\right)!}
The factorial of 16 is 20922789888000.
\frac{20922789888000}{40320\left(16-8\right)!}
The factorial of 8 is 40320.
\frac{20922789888000}{40320\times 8!}
Subtract 8 from 16 to get 8.
\frac{20922789888000}{40320\times 40320}
The factorial of 8 is 40320.
\frac{20922789888000}{1625702400}
Multiply 40320 and 40320 to get 1625702400.
12870
Divide 20922789888000 by 1625702400 to get 12870.