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Evaluate
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Differentiate w.r.t. x
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\frac{-10x}{4\times 40}
Express \frac{\frac{-10x}{4}}{40} as a single fraction.
\frac{-x}{2\times 8}
Cancel out 2\times 5 in both numerator and denominator.
\frac{-x}{16}
Multiply 2 and 8 to get 16.