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\frac{\left(-\left(-x\right)^{2}\left(y^{3}\right)^{2}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Expand \left(\left(-x\right)y^{3}\right)^{2}.
\frac{\left(-\left(-x\right)^{2}y^{6}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\left(-x^{2}y^{6}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Calculate -x to the power of 2 and get x^{2}.
\frac{\left(-x^{2}y^{6}\right)\left(-x\right)^{3}y^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Expand \left(\left(-x\right)y\right)^{3}.
\frac{\left(-x\right)^{3}\left(-x^{2}y^{6}\right)}{\left(-x^{2}\right)^{3}y^{7}}
Cancel out y^{3} in both numerator and denominator.
\frac{-x^{2}\left(-x\right)^{3}y^{6}}{\left(-x^{2}\right)^{3}y^{7}}
Factor the expressions that are not already factored.
\frac{-x^{2}\left(-x\right)^{3}}{y\left(-x^{2}\right)^{3}}
Cancel out y^{6} in both numerator and denominator.
\frac{x^{5}}{-yx^{6}}
Expand the expression.
\frac{1}{-xy}
Cancel out x^{5} in both numerator and denominator.
\frac{\left(-\left(-x\right)^{2}\left(y^{3}\right)^{2}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Expand \left(\left(-x\right)y^{3}\right)^{2}.
\frac{\left(-\left(-x\right)^{2}y^{6}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{\left(-x^{2}y^{6}\right)\left(\left(-x\right)y\right)^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Calculate -x to the power of 2 and get x^{2}.
\frac{\left(-x^{2}y^{6}\right)\left(-x\right)^{3}y^{3}}{\left(-x^{2}\right)^{3}y^{10}}
Expand \left(\left(-x\right)y\right)^{3}.
\frac{\left(-x\right)^{3}\left(-x^{2}y^{6}\right)}{\left(-x^{2}\right)^{3}y^{7}}
Cancel out y^{3} in both numerator and denominator.
\frac{-x^{2}\left(-x\right)^{3}y^{6}}{\left(-x^{2}\right)^{3}y^{7}}
Factor the expressions that are not already factored.
\frac{-x^{2}\left(-x\right)^{3}}{y\left(-x^{2}\right)^{3}}
Cancel out y^{6} in both numerator and denominator.
\frac{x^{5}}{-yx^{6}}
Expand the expression.
\frac{1}{-xy}
Cancel out x^{5} in both numerator and denominator.