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\frac{6^{-3}\left(-2\right)^{-6}\times 6^{3}\left(-2\right)^{5}}{\left(\left(-2\right)^{4}\times 6^{2}\right)^{-2}}
To multiply powers of the same base, add their exponents. Add -5 and 2 to get -3.
\frac{\left(-2\right)^{-6}\left(-2\right)^{5}}{\left(\left(-2\right)^{4}\times 6^{2}\right)^{-2}}
Multiply 6^{-3} and 6^{3} to get 1.
\frac{\left(-2\right)^{-1}}{\left(\left(-2\right)^{4}\times 6^{2}\right)^{-2}}
To multiply powers of the same base, add their exponents. Add -6 and 5 to get -1.
\frac{-\frac{1}{2}}{\left(\left(-2\right)^{4}\times 6^{2}\right)^{-2}}
Calculate -2 to the power of -1 and get -\frac{1}{2}.
\frac{-\frac{1}{2}}{\left(16\times 6^{2}\right)^{-2}}
Calculate -2 to the power of 4 and get 16.
\frac{-\frac{1}{2}}{\left(16\times 36\right)^{-2}}
Calculate 6 to the power of 2 and get 36.
\frac{-\frac{1}{2}}{576^{-2}}
Multiply 16 and 36 to get 576.
\frac{-\frac{1}{2}}{\frac{1}{331776}}
Calculate 576 to the power of -2 and get \frac{1}{331776}.
-\frac{1}{2}\times 331776
Divide -\frac{1}{2} by \frac{1}{331776} by multiplying -\frac{1}{2} by the reciprocal of \frac{1}{331776}.
-165888
Multiply -\frac{1}{2} and 331776 to get -165888.