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\frac{\frac{1}{64}-2^{6}}{2^{-8}}
Calculate 2 to the power of -6 and get \frac{1}{64}.
\frac{\frac{1}{64}-64}{2^{-8}}
Calculate 2 to the power of 6 and get 64.
\frac{-\frac{4095}{64}}{2^{-8}}
Subtract 64 from \frac{1}{64} to get -\frac{4095}{64}.
\frac{-\frac{4095}{64}}{\frac{1}{256}}
Calculate 2 to the power of -8 and get \frac{1}{256}.
-\frac{4095}{64}\times 256
Divide -\frac{4095}{64} by \frac{1}{256} by multiplying -\frac{4095}{64} by the reciprocal of \frac{1}{256}.
-16380
Multiply -\frac{4095}{64} and 256 to get -16380.