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\frac{2^{-4}\times 4^{2}\times 3^{-1}\times 9^{-1}}{2^{-5}\times 8\times 3^{-3}\times 9}
To multiply powers of the same base, add their exponents. Add 1 and -2 to get -1.
\frac{2^{1}\times 3^{2}\times 4^{2}\times \frac{1}{9}}{8\times 9}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{2^{1}\times 3^{2}\times 4^{2}}{8\times 9^{2}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{2\times 3^{2}\times 4^{2}}{8\times 9^{2}}
Calculate 2 to the power of 1 and get 2.
\frac{2\times 9\times 4^{2}}{8\times 9^{2}}
Calculate 3 to the power of 2 and get 9.
\frac{18\times 4^{2}}{8\times 9^{2}}
Multiply 2 and 9 to get 18.
\frac{18\times 16}{8\times 9^{2}}
Calculate 4 to the power of 2 and get 16.
\frac{288}{8\times 9^{2}}
Multiply 18 and 16 to get 288.
\frac{288}{8\times 81}
Calculate 9 to the power of 2 and get 81.
\frac{288}{648}
Multiply 8 and 81 to get 648.
\frac{4}{9}
Reduce the fraction \frac{288}{648} to lowest terms by extracting and canceling out 72.