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\frac{-243\times 8^{3}\times 2^{5}}{3^{2}\times 4^{4}}
Calculate -3 to the power of 5 and get -243.
\frac{-243\times 512\times 2^{5}}{3^{2}\times 4^{4}}
Calculate 8 to the power of 3 and get 512.
\frac{-124416\times 2^{5}}{3^{2}\times 4^{4}}
Multiply -243 and 512 to get -124416.
\frac{-124416\times 32}{3^{2}\times 4^{4}}
Calculate 2 to the power of 5 and get 32.
\frac{-3981312}{3^{2}\times 4^{4}}
Multiply -124416 and 32 to get -3981312.
\frac{-3981312}{9\times 4^{4}}
Calculate 3 to the power of 2 and get 9.
\frac{-3981312}{9\times 256}
Calculate 4 to the power of 4 and get 256.
\frac{-3981312}{2304}
Multiply 9 and 256 to get 2304.
-1728
Divide -3981312 by 2304 to get -1728.