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\frac{4\left(-3\right)^{5}\times 2^{4}}{9\left(-2^{7}\right)\times 9^{12}}
Cancel out 2 in both numerator and denominator.
\frac{4\left(-243\right)\times 2^{4}}{9\left(-2^{7}\right)\times 9^{12}}
Calculate -3 to the power of 5 and get -243.
\frac{-972\times 2^{4}}{9\left(-2^{7}\right)\times 9^{12}}
Multiply 4 and -243 to get -972.
\frac{-972\times 16}{9\left(-2^{7}\right)\times 9^{12}}
Calculate 2 to the power of 4 and get 16.
\frac{-15552}{9\left(-2^{7}\right)\times 9^{12}}
Multiply -972 and 16 to get -15552.
\frac{-15552}{9^{13}\left(-2^{7}\right)}
To multiply powers of the same base, add their exponents. Add 1 and 12 to get 13.
\frac{-15552}{2541865828329\left(-2^{7}\right)}
Calculate 9 to the power of 13 and get 2541865828329.
\frac{-15552}{2541865828329\left(-128\right)}
Calculate 2 to the power of 7 and get 128.
\frac{-15552}{-325358826026112}
Multiply 2541865828329 and -128 to get -325358826026112.
\frac{1}{20920706406}
Reduce the fraction \frac{-15552}{-325358826026112} to lowest terms by extracting and canceling out -15552.