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\frac{2^{-10}\times 2^{-6}}{2^{-18}}\times \left(\frac{1}{2}\right)^{3}
To raise a power to another power, multiply the exponents. Multiply -5 and 2 to get -10.
\frac{2^{-16}}{2^{-18}}\times \left(\frac{1}{2}\right)^{3}
To multiply powers of the same base, add their exponents. Add -10 and -6 to get -16.
2^{2}\times \left(\frac{1}{2}\right)^{3}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent. Subtract -18 from -16 to get 2.
4\times \left(\frac{1}{2}\right)^{3}
Calculate 2 to the power of 2 and get 4.
4\times \frac{1}{8}
Calculate \frac{1}{2} to the power of 3 and get \frac{1}{8}.
\frac{1}{2}
Multiply 4 and \frac{1}{8} to get \frac{1}{2}.