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\frac{\left(\frac{64\times 27}{-81}\right)^{3}}{\left(\frac{12\times 3^{5}}{9}\right)^{2}}
Calculate 3 to the power of 3 and get 27.
\frac{\left(\frac{1728}{-81}\right)^{3}}{\left(\frac{12\times 3^{5}}{9}\right)^{2}}
Multiply 64 and 27 to get 1728.
\frac{\left(-\frac{64}{3}\right)^{3}}{\left(\frac{12\times 3^{5}}{9}\right)^{2}}
Reduce the fraction \frac{1728}{-81} to lowest terms by extracting and canceling out 27.
\frac{-\frac{262144}{27}}{\left(\frac{12\times 3^{5}}{9}\right)^{2}}
Calculate -\frac{64}{3} to the power of 3 and get -\frac{262144}{27}.
\frac{-\frac{262144}{27}}{\left(\frac{12\times 243}{9}\right)^{2}}
Calculate 3 to the power of 5 and get 243.
\frac{-\frac{262144}{27}}{\left(\frac{2916}{9}\right)^{2}}
Multiply 12 and 243 to get 2916.
\frac{-\frac{262144}{27}}{324^{2}}
Divide 2916 by 9 to get 324.
\frac{-\frac{262144}{27}}{104976}
Calculate 324 to the power of 2 and get 104976.
\frac{-262144}{27\times 104976}
Express \frac{-\frac{262144}{27}}{104976} as a single fraction.
\frac{-262144}{2834352}
Multiply 27 and 104976 to get 2834352.
-\frac{16384}{177147}
Reduce the fraction \frac{-262144}{2834352} to lowest terms by extracting and canceling out 16.