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\frac{-\left(-x^{2}+1\right)\left(x^{2}-8x+16\right)}{\left(-x^{2}+1\right)\left(x^{2}-4x\right)}
Extract the negative sign in x^{2}-1.
\frac{-\left(x^{2}-8x+16\right)}{x^{2}-4x}
Cancel out -x^{2}+1 in both numerator and denominator.
\frac{-\left(x-4\right)^{2}}{x\left(x-4\right)}
Factor the expressions that are not already factored.
\frac{-\left(x-4\right)}{x}
Cancel out x-4 in both numerator and denominator.
\frac{-x+4}{x}
Expand the expression.
\frac{-\left(-x^{2}+1\right)\left(x^{2}-8x+16\right)}{\left(-x^{2}+1\right)\left(x^{2}-4x\right)}
Extract the negative sign in x^{2}-1.
\frac{-\left(x^{2}-8x+16\right)}{x^{2}-4x}
Cancel out -x^{2}+1 in both numerator and denominator.
\frac{-\left(x-4\right)^{2}}{x\left(x-4\right)}
Factor the expressions that are not already factored.
\frac{-\left(x-4\right)}{x}
Cancel out x-4 in both numerator and denominator.
\frac{-x+4}{x}
Expand the expression.