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Differentiate w.r.t. x
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\frac{\frac{35x^{3}y^{3}\times 7xy}{8p^{5}q^{4}\times 64pq}}{\frac{8p^{4}y^{4}}{5x^{2}y^{2}}}
Multiply \frac{35x^{3}y^{3}}{8p^{5}q^{4}} times \frac{7xy}{64pq} by multiplying numerator times numerator and denominator times denominator.
\frac{\frac{35x^{3}y^{3}\times 7xy}{8p^{5}q^{4}\times 64pq}}{\frac{8y^{2}p^{4}}{5x^{2}}}
Cancel out y^{2} in both numerator and denominator.
\frac{35x^{3}y^{3}\times 7xy\times 5x^{2}}{8p^{5}q^{4}\times 64pq\times 8y^{2}p^{4}}
Divide \frac{35x^{3}y^{3}\times 7xy}{8p^{5}q^{4}\times 64pq} by \frac{8y^{2}p^{4}}{5x^{2}} by multiplying \frac{35x^{3}y^{3}\times 7xy}{8p^{5}q^{4}\times 64pq} by the reciprocal of \frac{8y^{2}p^{4}}{5x^{2}}.
\frac{5\times 7\times 35xyyx^{2}x^{3}}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
Cancel out y^{2} in both numerator and denominator.
\frac{5\times 7\times 35x^{3}yyx^{3}}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
To multiply powers of the same base, add their exponents. Add 1 and 2 to get 3.
\frac{5\times 7\times 35x^{6}yy}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
To multiply powers of the same base, add their exponents. Add 3 and 3 to get 6.
\frac{5\times 7\times 35x^{6}y^{2}}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
Multiply y and y to get y^{2}.
\frac{35\times 35x^{6}y^{2}}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
Multiply 5 and 7 to get 35.
\frac{1225x^{6}y^{2}}{8\times 8\times 64pqp^{4}q^{4}p^{5}}
Multiply 35 and 35 to get 1225.
\frac{1225x^{6}y^{2}}{8\times 8\times 64p^{5}qq^{4}p^{5}}
To multiply powers of the same base, add their exponents. Add 1 and 4 to get 5.
\frac{1225x^{6}y^{2}}{8\times 8\times 64p^{10}qq^{4}}
To multiply powers of the same base, add their exponents. Add 5 and 5 to get 10.
\frac{1225x^{6}y^{2}}{8\times 8\times 64p^{10}q^{5}}
To multiply powers of the same base, add their exponents. Add 1 and 4 to get 5.
\frac{1225x^{6}y^{2}}{64\times 64p^{10}q^{5}}
Multiply 8 and 8 to get 64.
\frac{1225x^{6}y^{2}}{4096p^{10}q^{5}}
Multiply 64 and 64 to get 4096.