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16y_{0}\left(-\frac{1}{4}\right)+1=0
Multiply both sides of the equation by 16, the least common multiple of 4,16.
\frac{16\left(-1\right)}{4}y_{0}+1=0
Express 16\left(-\frac{1}{4}\right) as a single fraction.
\frac{-16}{4}y_{0}+1=0
Multiply 16 and -1 to get -16.
-4y_{0}+1=0
Divide -16 by 4 to get -4.
-4y_{0}=-1
Subtract 1 from both sides. Anything subtracted from zero gives its negation.
y_{0}=\frac{-1}{-4}
Divide both sides by -4.
y_{0}=\frac{1}{4}
Fraction \frac{-1}{-4} can be simplified to \frac{1}{4} by removing the negative sign from both the numerator and the denominator.