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\left(x-4\right)\left(x-2\right)=\left(x+2\right)\left(x+8\right)
Variable x cannot be equal to any of the values -2,4 since division by zero is not defined. Multiply both sides of the equation by \left(x-4\right)\left(x+2\right), the least common multiple of x+2,x-4.
x^{2}-6x+8=\left(x+2\right)\left(x+8\right)
Use the distributive property to multiply x-4 by x-2 and combine like terms.
x^{2}-6x+8=x^{2}+10x+16
Use the distributive property to multiply x+2 by x+8 and combine like terms.
x^{2}-6x+8-x^{2}=10x+16
Subtract x^{2} from both sides.
-6x+8=10x+16
Combine x^{2} and -x^{2} to get 0.
-6x+8-10x=16
Subtract 10x from both sides.
-16x+8=16
Combine -6x and -10x to get -16x.
-16x=16-8
Subtract 8 from both sides.
-16x=8
Subtract 8 from 16 to get 8.
x=\frac{8}{-16}
Divide both sides by -16.
x=-\frac{1}{2}
Reduce the fraction \frac{8}{-16} to lowest terms by extracting and canceling out 8.