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Differentiate w.r.t. x
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\frac{x}{\left(x-5\right)\left(x+5\right)}-\frac{4}{\left(x-5\right)^{2}}
Factor x^{2}-25. Factor x^{2}-10x+25.
\frac{x\left(x-5\right)}{\left(x+5\right)\left(x-5\right)^{2}}-\frac{4\left(x+5\right)}{\left(x+5\right)\left(x-5\right)^{2}}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(x-5\right)\left(x+5\right) and \left(x-5\right)^{2} is \left(x+5\right)\left(x-5\right)^{2}. Multiply \frac{x}{\left(x-5\right)\left(x+5\right)} times \frac{x-5}{x-5}. Multiply \frac{4}{\left(x-5\right)^{2}} times \frac{x+5}{x+5}.
\frac{x\left(x-5\right)-4\left(x+5\right)}{\left(x+5\right)\left(x-5\right)^{2}}
Since \frac{x\left(x-5\right)}{\left(x+5\right)\left(x-5\right)^{2}} and \frac{4\left(x+5\right)}{\left(x+5\right)\left(x-5\right)^{2}} have the same denominator, subtract them by subtracting their numerators.
\frac{x^{2}-5x-4x-20}{\left(x+5\right)\left(x-5\right)^{2}}
Do the multiplications in x\left(x-5\right)-4\left(x+5\right).
\frac{x^{2}-9x-20}{\left(x+5\right)\left(x-5\right)^{2}}
Combine like terms in x^{2}-5x-4x-20.
\frac{x^{2}-9x-20}{x^{3}-5x^{2}-25x+125}
Expand \left(x+5\right)\left(x-5\right)^{2}.