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Differentiate w.r.t. x
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\frac{x\left(x+5\right)}{\left(x+5\right)\left(2x+1\right)}-\frac{3\left(2x+1\right)}{\left(x+5\right)\left(2x+1\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of 2x+1 and x+5 is \left(x+5\right)\left(2x+1\right). Multiply \frac{x}{2x+1} times \frac{x+5}{x+5}. Multiply \frac{3}{x+5} times \frac{2x+1}{2x+1}.
\frac{x\left(x+5\right)-3\left(2x+1\right)}{\left(x+5\right)\left(2x+1\right)}
Since \frac{x\left(x+5\right)}{\left(x+5\right)\left(2x+1\right)} and \frac{3\left(2x+1\right)}{\left(x+5\right)\left(2x+1\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{x^{2}+5x-6x-3}{\left(x+5\right)\left(2x+1\right)}
Do the multiplications in x\left(x+5\right)-3\left(2x+1\right).
\frac{x^{2}-x-3}{\left(x+5\right)\left(2x+1\right)}
Combine like terms in x^{2}+5x-6x-3.
\frac{x^{2}-x-3}{2x^{2}+11x+5}
Expand \left(x+5\right)\left(2x+1\right).