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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{1}{1}x^{-2-5})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(x^{-7})
Do the arithmetic.
-7x^{-7-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-7x^{-8}
Do the arithmetic.
\frac{1}{x^{7}}
Rewrite x^{5} as x^{-2}x^{7}. Cancel out x^{-2} in both numerator and denominator.