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2\left(x+3\right)+4\left(2x-1\right)+3=x-5-8
Multiply both sides of the equation by 12, the least common multiple of 6,3,4,12.
2x+6+4\left(2x-1\right)+3=x-5-8
Use the distributive property to multiply 2 by x+3.
2x+6+8x-4+3=x-5-8
Use the distributive property to multiply 4 by 2x-1.
10x+6-4+3=x-5-8
Combine 2x and 8x to get 10x.
10x+2+3=x-5-8
Subtract 4 from 6 to get 2.
10x+5=x-5-8
Add 2 and 3 to get 5.
10x+5=x-13
Subtract 8 from -5 to get -13.
10x+5-x=-13
Subtract x from both sides.
9x+5=-13
Combine 10x and -x to get 9x.
9x=-13-5
Subtract 5 from both sides.
9x=-18
Subtract 5 from -13 to get -18.
x=\frac{-18}{9}
Divide both sides by 9.
x=-2
Divide -18 by 9 to get -2.