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6\left(x+3\right)=12\times 4-3\left(x+1\right)-4\left(2-5x\right)
Multiply both sides of the equation by 12, the least common multiple of 2,4,3.
6x+18=12\times 4-3\left(x+1\right)-4\left(2-5x\right)
Use the distributive property to multiply 6 by x+3.
6x+18=48-3\left(x+1\right)-4\left(2-5x\right)
Multiply 12 and 4 to get 48.
6x+18=48-3x-3-4\left(2-5x\right)
Use the distributive property to multiply -3 by x+1.
6x+18=45-3x-4\left(2-5x\right)
Subtract 3 from 48 to get 45.
6x+18=45-3x-8+20x
Use the distributive property to multiply -4 by 2-5x.
6x+18=37-3x+20x
Subtract 8 from 45 to get 37.
6x+18=37+17x
Combine -3x and 20x to get 17x.
6x+18-17x=37
Subtract 17x from both sides.
-11x+18=37
Combine 6x and -17x to get -11x.
-11x=37-18
Subtract 18 from both sides.
-11x=19
Subtract 18 from 37 to get 19.
x=\frac{19}{-11}
Divide both sides by -11.
x=-\frac{19}{11}
Fraction \frac{19}{-11} can be rewritten as -\frac{19}{11} by extracting the negative sign.