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Differentiate w.r.t. q
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\frac{qr^{2}s^{8}t^{3}}{q^{6}r^{0}s^{6}t^{-3}r^{9}s^{6}t^{0}}
To multiply powers of the same base, add their exponents. Add 5 and 1 to get 6.
\frac{qr^{2}s^{8}t^{3}}{q^{6}r^{9}s^{6}t^{-3}s^{6}t^{0}}
To multiply powers of the same base, add their exponents. Add 0 and 9 to get 9.
\frac{qr^{2}s^{8}t^{3}}{q^{6}r^{9}s^{12}t^{-3}t^{0}}
To multiply powers of the same base, add their exponents. Add 6 and 6 to get 12.
\frac{qr^{2}s^{8}t^{3}}{q^{6}r^{9}s^{12}t^{-3}}
To multiply powers of the same base, add their exponents. Add -3 and 0 to get -3.
\frac{t^{3}}{t^{-3}s^{4}q^{5}r^{7}}
Cancel out qr^{2}s^{8} in both numerator and denominator.
\frac{t^{6}}{s^{4}q^{5}r^{7}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}q}(\frac{r^{2}t^{3}s^{8}t^{3}}{qr^{0}t^{0}s^{6}s^{6}r^{9}}q^{1-5})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}q}(\frac{t^{6}}{qs^{4}r^{7}}q^{-4})
Do the arithmetic.
-4\times \frac{t^{6}}{qs^{4}r^{7}}q^{-4-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{4t^{6}}{qs^{4}r^{7}}\right)q^{-5}
Do the arithmetic.