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Differentiate w.r.t. n
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\frac{\mathrm{d}}{\mathrm{d}n}(\frac{1}{1}n^{-3-3})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}n}(n^{-6})
Do the arithmetic.
-6n^{-6-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-6n^{-7}
Do the arithmetic.
\frac{1}{n^{6}}
Rewrite n^{3} as n^{-3}n^{6}. Cancel out n^{-3} in both numerator and denominator.