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Differentiate w.r.t. m
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\frac{\mathrm{d}}{\mathrm{d}m}(\frac{1}{n^{2}p^{8}p^{3}n^{5}}m^{-1-4})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}m}(\frac{1}{n^{7}p^{11}}m^{-5})
Do the arithmetic.
-5\times \frac{1}{n^{7}p^{11}}m^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{5}{n^{7}p^{11}}\right)m^{-6}
Do the arithmetic.
\frac{1}{m^{5}n^{7}p^{11}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.