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Differentiate w.r.t. b
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\frac{b^{2}}{1}\left(-\frac{10a}{16ab}\right)\times \frac{2}{b^{3}}
Calculate 1 to the power of 3 and get 1.
b^{2}\left(-\frac{10a}{16ab}\right)\times \frac{2}{b^{3}}
Anything divided by one gives itself.
b^{2}\left(-\frac{5}{8b}\right)\times \frac{2}{b^{3}}
Cancel out 2a in both numerator and denominator.
\frac{-b^{2}\times 5}{8b}\times \frac{2}{b^{3}}
Express b^{2}\left(-\frac{5}{8b}\right) as a single fraction.
\frac{-5b}{8}\times \frac{2}{b^{3}}
Cancel out b in both numerator and denominator.
\frac{-5b\times 2}{8b^{3}}
Multiply \frac{-5b}{8} times \frac{2}{b^{3}} by multiplying numerator times numerator and denominator times denominator.
\frac{-5}{4b^{2}}
Cancel out 2b in both numerator and denominator.