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Differentiate w.r.t. b
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\frac{\mathrm{d}}{\mathrm{d}b}(\frac{1}{1}b^{-4-\left(-6\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}b}(b^{2})
Do the arithmetic.
2b^{2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
2b^{1}
Do the arithmetic.
2b
For any term t, t^{1}=t.
b^{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent. Subtract -6 from -4 to get 2.