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Differentiate w.r.t. B
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\frac{A^{-2}BC^{-4}D^{5}}{AB^{2}C^{-2}D}E^{2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent. Subtract -1 from 1 to get 2.
\frac{C^{-4}A^{-2}D^{4}}{C^{-2}AB}E^{2}
Cancel out BD in both numerator and denominator.
\frac{D^{4}}{BC^{2}A^{3}}E^{2}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{D^{4}E^{2}}{BC^{2}A^{3}}
Express \frac{D^{4}}{BC^{2}A^{3}}E^{2} as a single fraction.