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\frac{20n\left(m+2n\right)\left(-m+2n\right)k^{2}m^{2}}{16mnk^{2}\left(m-2n\right)^{2}}
Factor the expressions that are not already factored.
\frac{5m\left(m+2n\right)\left(-m+2n\right)}{4\left(m-2n\right)^{2}}
Cancel out 4mnk^{2} in both numerator and denominator.
\frac{-5m^{3}+20mn^{2}}{4m^{2}-16mn+16n^{2}}
Expand the expression.
\frac{5m\left(m-2n\right)\left(-m-2n\right)}{4\left(m-2n\right)^{2}}
Factor the expressions that are not already factored.
\frac{5m\left(-m-2n\right)}{4\left(m-2n\right)}
Cancel out m-2n in both numerator and denominator.
\frac{-5m^{2}-10mn}{4m-8n}
Expand the expression.
\frac{20n\left(m+2n\right)\left(-m+2n\right)k^{2}m^{2}}{16mnk^{2}\left(m-2n\right)^{2}}
Factor the expressions that are not already factored.
\frac{5m\left(m+2n\right)\left(-m+2n\right)}{4\left(m-2n\right)^{2}}
Cancel out 4mnk^{2} in both numerator and denominator.
\frac{-5m^{3}+20mn^{2}}{4m^{2}-16mn+16n^{2}}
Expand the expression.
\frac{5m\left(m-2n\right)\left(-m-2n\right)}{4\left(m-2n\right)^{2}}
Factor the expressions that are not already factored.
\frac{5m\left(-m-2n\right)}{4\left(m-2n\right)}
Cancel out m-2n in both numerator and denominator.
\frac{-5m^{2}-10mn}{4m-8n}
Expand the expression.