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Evaluate
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Differentiate w.r.t. a
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\frac{8c^{-3}a^{2}}{a^{-3}c^{6}}
Cancel out b^{4} in both numerator and denominator.
\frac{8c^{-3}a^{5}}{c^{6}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{8a^{5}}{c^{9}}
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{8b^{4}}{c^{3}b^{4}c^{6}}a^{2-\left(-3\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}a}(\frac{8}{c^{9}}a^{5})
Do the arithmetic.
5\times \frac{8}{c^{9}}a^{5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{40}{c^{9}}a^{4}
Do the arithmetic.