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\frac{4\left(-2y^{2}x^{3}\right)^{2}}{x^{-3}y^{-2}}
Cancel out 2 in both numerator and denominator.
\frac{4\left(-2\right)^{2}\left(y^{2}\right)^{2}\left(x^{3}\right)^{2}}{x^{-3}y^{-2}}
Expand \left(-2y^{2}x^{3}\right)^{2}.
\frac{4\left(-2\right)^{2}y^{4}\left(x^{3}\right)^{2}}{x^{-3}y^{-2}}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
\frac{4\left(-2\right)^{2}y^{4}x^{6}}{x^{-3}y^{-2}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{4\times 4y^{4}x^{6}}{x^{-3}y^{-2}}
Calculate -2 to the power of 2 and get 4.
\frac{16y^{4}x^{6}}{x^{-3}y^{-2}}
Multiply 4 and 4 to get 16.
16y^{6}x^{9}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{4\left(-2y^{2}x^{3}\right)^{2}}{x^{-3}y^{-2}}
Cancel out 2 in both numerator and denominator.
\frac{4\left(-2\right)^{2}\left(y^{2}\right)^{2}\left(x^{3}\right)^{2}}{x^{-3}y^{-2}}
Expand \left(-2y^{2}x^{3}\right)^{2}.
\frac{4\left(-2\right)^{2}y^{4}\left(x^{3}\right)^{2}}{x^{-3}y^{-2}}
To raise a power to another power, multiply the exponents. Multiply 2 and 2 to get 4.
\frac{4\left(-2\right)^{2}y^{4}x^{6}}{x^{-3}y^{-2}}
To raise a power to another power, multiply the exponents. Multiply 3 and 2 to get 6.
\frac{4\times 4y^{4}x^{6}}{x^{-3}y^{-2}}
Calculate -2 to the power of 2 and get 4.
\frac{16y^{4}x^{6}}{x^{-3}y^{-2}}
Multiply 4 and 4 to get 16.
16y^{6}x^{9}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.