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\frac{16x^{3}y^{2}-24x^{2}y^{3}+144xy^{3}z+9xy^{4}+576xy^{2}z^{2}-192x^{2}y^{2}z}{18}
Factor out \frac{1}{18}.
xy^{2}\left(16x^{2}-24xy+144yz+9y^{2}+576z^{2}-192xz\right)
Consider 16x^{3}y^{2}-24x^{2}y^{3}+144xy^{3}z+9xy^{4}+576xy^{2}z^{2}-192x^{2}y^{2}z. Factor out xy^{2}.
\left(4x-3y-24z\right)^{2}
Consider 16x^{2}-24xy+144yz+9y^{2}+576z^{2}-192xz. Use the perfect square formula, a^{2}+b^{2}+c^{2}+2ab+2ac+2bc=\left(a+b+c\right)^{2}, where a=4x, b=-3y and c=-24z.
\frac{xy^{2}\left(4x-3y-24z\right)^{2}}{18}
Rewrite the complete factored expression.