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\frac{8\left(-25\right)}{5\times 16}
Multiply \frac{8}{5} times -\frac{25}{16} by multiplying numerator times numerator and denominator times denominator.
\frac{-200}{80}
Do the multiplications in the fraction \frac{8\left(-25\right)}{5\times 16}.
-\frac{5}{2}
Reduce the fraction \frac{-200}{80} to lowest terms by extracting and canceling out 40.