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Differentiate w.r.t. E
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\frac{8\times 10000000}{\pi \times 5\times 193\times 115}E\times 1\times \frac{-100^{2}}{2\times 115^{2}}
Calculate 10 to the power of 7 and get 10000000.
\frac{80000000}{\pi \times 5\times 193\times 115}E\times 1\times \frac{-100^{2}}{2\times 115^{2}}
Multiply 8 and 10000000 to get 80000000.
\frac{80000000}{\pi \times 965\times 115}E\times 1\times \frac{-100^{2}}{2\times 115^{2}}
Multiply 5 and 193 to get 965.
\frac{80000000}{\pi \times 110975}E\times 1\times \frac{-100^{2}}{2\times 115^{2}}
Multiply 965 and 115 to get 110975.
\frac{80000000}{\pi \times 110975}E\times 1\times \frac{-10000}{2\times 115^{2}}
Calculate 100 to the power of 2 and get 10000.
\frac{80000000}{\pi \times 110975}E\times 1\times \frac{-10000}{2\times 13225}
Calculate 115 to the power of 2 and get 13225.
\frac{80000000}{\pi \times 110975}E\times 1\times \frac{-10000}{26450}
Multiply 2 and 13225 to get 26450.
\frac{80000000}{\pi \times 110975}E\times 1\left(-\frac{200}{529}\right)
Reduce the fraction \frac{-10000}{26450} to lowest terms by extracting and canceling out 50.
\frac{80000000}{\pi \times 110975}E\left(-\frac{200}{529}\right)
Multiply 1 and -\frac{200}{529} to get -\frac{200}{529}.
\frac{80000000E}{\pi \times 110975}\left(-\frac{200}{529}\right)
Express \frac{80000000}{\pi \times 110975}E as a single fraction.
\frac{3200000E}{4439\pi }\left(-\frac{200}{529}\right)
Cancel out 25 in both numerator and denominator.
\frac{-3200000E\times 200}{4439\pi \times 529}
Multiply \frac{3200000E}{4439\pi } times -\frac{200}{529} by multiplying numerator times numerator and denominator times denominator.
\frac{-640000000E}{4439\pi \times 529}
Multiply -3200000 and 200 to get -640000000.
\frac{-640000000E}{2348231\pi }
Multiply 4439 and 529 to get 2348231.