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Evaluate
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Differentiate w.r.t. x
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\frac{72^{1}x^{5}y^{4}}{\left(-36\right)^{1}x^{2}y^{2}}
Use the rules of exponents to simplify the expression.
\frac{72^{1}}{\left(-36\right)^{1}}x^{5-2}y^{4-2}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{72^{1}}{\left(-36\right)^{1}}x^{3}y^{4-2}
Subtract 2 from 5.
\frac{72^{1}}{\left(-36\right)^{1}}x^{3}y^{2}
Subtract 2 from 4.
-2x^{3}y^{2}
Divide 72 by -36.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{72y^{4}}{-36y^{2}}x^{5-2})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\left(-2y^{2}\right)x^{3})
Do the arithmetic.
3\left(-2y^{2}\right)x^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-6y^{2}\right)x^{2}
Do the arithmetic.