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\frac{64x^{3}-27}{4x^{2}-36}\times \frac{4\left(x+3\right)}{4\left(16x^{2}+12x+9\right)}
Factor the expressions that are not already factored in \frac{4x+12}{64x^{2}+48x+36}.
\frac{64x^{3}-27}{4x^{2}-36}\times \frac{x+3}{16x^{2}+12x+9}
Cancel out 4 in both numerator and denominator.
\frac{\left(64x^{3}-27\right)\left(x+3\right)}{\left(4x^{2}-36\right)\left(16x^{2}+12x+9\right)}
Multiply \frac{64x^{3}-27}{4x^{2}-36} times \frac{x+3}{16x^{2}+12x+9} by multiplying numerator times numerator and denominator times denominator.
\frac{\left(4x-3\right)\left(x+3\right)\left(16x^{2}+12x+9\right)}{4\left(x-3\right)\left(x+3\right)\left(16x^{2}+12x+9\right)}
Factor the expressions that are not already factored.
\frac{4x-3}{4\left(x-3\right)}
Cancel out \left(x+3\right)\left(16x^{2}+12x+9\right) in both numerator and denominator.
\frac{4x-3}{4x-12}
Expand the expression.
\frac{64x^{3}-27}{4x^{2}-36}\times \frac{4\left(x+3\right)}{4\left(16x^{2}+12x+9\right)}
Factor the expressions that are not already factored in \frac{4x+12}{64x^{2}+48x+36}.
\frac{64x^{3}-27}{4x^{2}-36}\times \frac{x+3}{16x^{2}+12x+9}
Cancel out 4 in both numerator and denominator.
\frac{\left(64x^{3}-27\right)\left(x+3\right)}{\left(4x^{2}-36\right)\left(16x^{2}+12x+9\right)}
Multiply \frac{64x^{3}-27}{4x^{2}-36} times \frac{x+3}{16x^{2}+12x+9} by multiplying numerator times numerator and denominator times denominator.
\frac{\left(4x-3\right)\left(x+3\right)\left(16x^{2}+12x+9\right)}{4\left(x-3\right)\left(x+3\right)\left(16x^{2}+12x+9\right)}
Factor the expressions that are not already factored.
\frac{4x-3}{4\left(x-3\right)}
Cancel out \left(x+3\right)\left(16x^{2}+12x+9\right) in both numerator and denominator.
\frac{4x-3}{4x-12}
Expand the expression.