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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{5y^{3}y^{3}}{4}x^{-4-\left(-7\right)})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(\frac{5y^{6}}{4}x^{3})
Do the arithmetic.
3\times \frac{5y^{6}}{4}x^{3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\frac{15y^{6}}{4}x^{2}
Do the arithmetic.
\frac{5x^{3}y^{6}}{4}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.