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Differentiate w.r.t. u
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\left(5u^{0}\right)^{1}\times \frac{1}{5u^{8}}
Use the rules of exponents to simplify the expression.
5^{1}\left(u^{0}\right)^{1}\times \frac{1}{5}\times \frac{1}{u^{8}}
To raise the product of two or more numbers to a power, raise each number to the power and take their product.
5^{1}\times \frac{1}{5}\left(u^{0}\right)^{1}\times \frac{1}{u^{8}}
Use the Commutative Property of Multiplication.
5^{1}\times \frac{1}{5}u^{0}u^{8\left(-1\right)}
To raise a power to another power, multiply the exponents.
5^{1}\times \frac{1}{5}u^{0}u^{-8}
Multiply 8 times -1.
5^{1}\times \frac{1}{5}u^{-8}
To multiply powers of the same base, add their exponents.
5^{1-1}u^{-8}
To multiply powers of the same base, add their exponents.
5^{0}u^{-8}
Add the exponents 1 and -1.
1u^{-8}
For any term t except 0, t^{0}=1.
u^{-8}
For any term t, t\times 1=t and 1t=t.
\frac{5^{1}u^{0}}{5^{1}u^{8}}
Use the rules of exponents to simplify the expression.
5^{1-1}u^{-8}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
5^{0}u^{-8}
Subtract 1 from 1.
u^{-8}
For any number a except 0, a^{0}=1.
\frac{\mathrm{d}}{\mathrm{d}u}(\frac{u^{0}}{u^{8}})
Cancel out 5 in both numerator and denominator.
\frac{\mathrm{d}}{\mathrm{d}u}(\frac{1}{u^{8}})
To divide powers of the same base, subtract the numerator's exponent from the denominator's exponent.
-\left(u^{8}\right)^{-1-1}\frac{\mathrm{d}}{\mathrm{d}u}(u^{8})
If F is the composition of two differentiable functions f\left(u\right) and u=g\left(x\right), that is, if F\left(x\right)=f\left(g\left(x\right)\right), then the derivative of F is the derivative of f with respect to u times the derivative of g with respect to x, that is, \frac{\mathrm{d}}{\mathrm{d}x}(F)\left(x\right)=\frac{\mathrm{d}}{\mathrm{d}x}(f)\left(g\left(x\right)\right)\frac{\mathrm{d}}{\mathrm{d}x}(g)\left(x\right).
-\left(u^{8}\right)^{-2}\times 8u^{8-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-8u^{7}\left(u^{8}\right)^{-2}
Simplify.