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\frac{5s}{\left(4s-5t\right)\left(4s+5t\right)}-\frac{s}{4s-5t}
Factor 16s^{2}-25t^{2}.
\frac{5s}{\left(4s-5t\right)\left(4s+5t\right)}-\frac{s\left(4s+5t\right)}{\left(4s-5t\right)\left(4s+5t\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of \left(4s-5t\right)\left(4s+5t\right) and 4s-5t is \left(4s-5t\right)\left(4s+5t\right). Multiply \frac{s}{4s-5t} times \frac{4s+5t}{4s+5t}.
\frac{5s-s\left(4s+5t\right)}{\left(4s-5t\right)\left(4s+5t\right)}
Since \frac{5s}{\left(4s-5t\right)\left(4s+5t\right)} and \frac{s\left(4s+5t\right)}{\left(4s-5t\right)\left(4s+5t\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{5s-4s^{2}-5st}{\left(4s-5t\right)\left(4s+5t\right)}
Do the multiplications in 5s-s\left(4s+5t\right).
\frac{5s-4s^{2}-5st}{16s^{2}-25t^{2}}
Expand \left(4s-5t\right)\left(4s+5t\right).