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Differentiate w.r.t. s
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\frac{\mathrm{d}}{\mathrm{d}s}(\frac{5ut^{8}}{5u^{4}t^{9}}s^{7-9})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}s}(\frac{1}{tu^{3}}s^{-2})
Do the arithmetic.
-2\times \frac{1}{tu^{3}}s^{-2-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-\frac{2}{tu^{3}}\right)s^{-3}
Do the arithmetic.
\frac{1}{ts^{2}u^{3}}
Cancel out 5us^{7}t^{8} in both numerator and denominator.