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\frac{5}{x+3}-\frac{4}{x\left(x+3\right)}+\frac{16}{x^{2}-4}
Factor x^{2}+3x.
\frac{5x}{x\left(x+3\right)}-\frac{4}{x\left(x+3\right)}+\frac{16}{x^{2}-4}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x+3 and x\left(x+3\right) is x\left(x+3\right). Multiply \frac{5}{x+3} times \frac{x}{x}.
\frac{5x-4}{x\left(x+3\right)}+\frac{16}{x^{2}-4}
Since \frac{5x}{x\left(x+3\right)} and \frac{4}{x\left(x+3\right)} have the same denominator, subtract them by subtracting their numerators.
\frac{5x-4}{x\left(x+3\right)}+\frac{16}{\left(x-2\right)\left(x+2\right)}
Factor x^{2}-4.
\frac{\left(5x-4\right)\left(x-2\right)\left(x+2\right)}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)}+\frac{16x\left(x+3\right)}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)}
To add or subtract expressions, expand them to make their denominators the same. Least common multiple of x\left(x+3\right) and \left(x-2\right)\left(x+2\right) is x\left(x-2\right)\left(x+2\right)\left(x+3\right). Multiply \frac{5x-4}{x\left(x+3\right)} times \frac{\left(x-2\right)\left(x+2\right)}{\left(x-2\right)\left(x+2\right)}. Multiply \frac{16}{\left(x-2\right)\left(x+2\right)} times \frac{x\left(x+3\right)}{x\left(x+3\right)}.
\frac{\left(5x-4\right)\left(x-2\right)\left(x+2\right)+16x\left(x+3\right)}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)}
Since \frac{\left(5x-4\right)\left(x-2\right)\left(x+2\right)}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)} and \frac{16x\left(x+3\right)}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)} have the same denominator, add them by adding their numerators.
\frac{5x^{3}-20x-4x^{2}+16+16x^{2}+48x}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)}
Do the multiplications in \left(5x-4\right)\left(x-2\right)\left(x+2\right)+16x\left(x+3\right).
\frac{5x^{3}+28x+12x^{2}+16}{x\left(x-2\right)\left(x+2\right)\left(x+3\right)}
Combine like terms in 5x^{3}-20x-4x^{2}+16+16x^{2}+48x.
\frac{5x^{3}+28x+12x^{2}+16}{x^{4}+3x^{3}-4x^{2}-12x}
Expand x\left(x-2\right)\left(x+2\right)\left(x+3\right).