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\frac{5}{12}+\left(\frac{5}{10}+\frac{6}{10}\right)\times \frac{-8}{3}
Least common multiple of 2 and 5 is 10. Convert \frac{1}{2} and \frac{3}{5} to fractions with denominator 10.
\frac{5}{12}+\frac{5+6}{10}\times \frac{-8}{3}
Since \frac{5}{10} and \frac{6}{10} have the same denominator, add them by adding their numerators.
\frac{5}{12}+\frac{11}{10}\times \frac{-8}{3}
Add 5 and 6 to get 11.
\frac{5}{12}+\frac{11}{10}\left(-\frac{8}{3}\right)
Fraction \frac{-8}{3} can be rewritten as -\frac{8}{3} by extracting the negative sign.
\frac{5}{12}+\frac{11\left(-8\right)}{10\times 3}
Multiply \frac{11}{10} times -\frac{8}{3} by multiplying numerator times numerator and denominator times denominator.
\frac{5}{12}+\frac{-88}{30}
Do the multiplications in the fraction \frac{11\left(-8\right)}{10\times 3}.
\frac{5}{12}-\frac{44}{15}
Reduce the fraction \frac{-88}{30} to lowest terms by extracting and canceling out 2.
\frac{25}{60}-\frac{176}{60}
Least common multiple of 12 and 15 is 60. Convert \frac{5}{12} and \frac{44}{15} to fractions with denominator 60.
\frac{25-176}{60}
Since \frac{25}{60} and \frac{176}{60} have the same denominator, subtract them by subtracting their numerators.
-\frac{151}{60}
Subtract 176 from 25 to get -151.