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Differentiate w.r.t. y
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\frac{\mathrm{d}}{\mathrm{d}y}(\frac{10}{2}y^{1-4})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}y}(5y^{-3})
Do the arithmetic.
-3\times 5y^{-3-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-15y^{-4}
Do the arithmetic.
\frac{5}{y^{3}}
Cancel out 2y in both numerator and denominator.