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Differentiate w.r.t. x
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\frac{\mathrm{d}}{\mathrm{d}x}(\frac{4y^{5}}{1}x^{2-7})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}x}(4y^{5}x^{-5})
Do the arithmetic.
-5\times 4y^{5}x^{-5-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
\left(-20y^{5}\right)x^{-6}
Do the arithmetic.
\frac{4y^{5}}{x^{5}}
Cancel out x^{2} in both numerator and denominator.