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Differentiate w.r.t. m
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\frac{\mathrm{d}}{\mathrm{d}m}(\frac{4}{1}m^{-\frac{1}{3}-\frac{4}{3}})
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.
\frac{\mathrm{d}}{\mathrm{d}m}(4m^{-\frac{5}{3}})
Do the arithmetic.
-\frac{5}{3}\times 4m^{-\frac{5}{3}-1}
The derivative of a polynomial is the sum of the derivatives of its terms. The derivative of a constant term is 0. The derivative of ax^{n} is nax^{n-1}.
-\frac{20}{3}m^{-\frac{8}{3}}
Do the arithmetic.