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Differentiate w.r.t. c
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\frac{4a^{2}c^{4}}{3b^{-2}c^{2}\times 4b^{-4}c^{-3}}
Multiply a and a^{-1} to get 1.
\frac{4a^{2}c^{4}}{3b^{-6}c^{2}\times 4c^{-3}}
To multiply powers of the same base, add their exponents. Add -2 and -4 to get -6.
\frac{4a^{2}c^{4}}{3b^{-6}c^{-1}\times 4}
To multiply powers of the same base, add their exponents. Add 2 and -3 to get -1.
\frac{a^{2}c^{4}}{3b^{-6}\times \frac{1}{c}}
Cancel out 4 in both numerator and denominator.
\frac{a^{2}c^{5}}{3b^{-6}}
To divide powers of the same base, subtract the denominator's exponent from the numerator's exponent.